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KMID : 1003219980040010210
Journal of Korean Oriental Chronic Disease
1998 Volume.4 No. 1 p.210 ~ p.222
Effects of the extract of Trigonellae Semen on erectile dysfunction
ÑÑÎÃòå/Kim, Kwang Jin
Ë©ïÞñÕ/ãéúèôÊ/ëÅôÉûÇ/ï÷òªô¸/ßïñ£ëÞ/ãéåâàð/Kang, Jeong Jun/Shin, Hyeon Chul/Yoon, Cheol Ho/Jeong, Ji Cheon/Seon, Jong Eun/Shin, Uk Seob
Abstract
The fallowing are the results of the experimental studies of Trigonellae Semen (TS) on the urethral nitrite level and the urethral nitric oxide synthase (NOS) activity in streptozotocin(STZ) induced diabetic rats.
In vitro, the urethral NOS activity was not noted in the level of Dose of extract prepared from TS. In vivo, the urethral NOS activity was increased in normal rats by dose and term of the extract prerared from TS. The urethral NOS activity decreased in STZ induced diabetic rats was increased as highly as normal group by the extract of TS. The level of urethral nitrite and gluthione was increased too. The level of urethral lipid peroxide increased in STZ induced diabetic rats was decreased as lowly as normal group by the extract of TS.
In conclusion, the extract of TS will be able to restore erectile dysfunction of STZ induced diabetic rats.
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